Mutations in Dna Essay Example for Free

Mutations in Dna Essay Although most mutations are either neutral or harmful they are also the raw material for evolution. Such mutations from alleles, alternate forms of a given gene that may produce differences in structure or function such as black, brown or blond hair in humans, or different mating calls in frogs. Stages of Mitosis~ 1)Parent cell. 2)Chromosomes make identical copies of themselves. 3)They line up along the centre. 4)They move apart. 5)Two daughter cells form with identical chromosomes to the parent cell. Homologous chromosomes have the same genes, but each homologue may have the same alleles of some genes and different alleles others. The cell cycle is tightly controlled. Both during the embryonic development and during the maintenance and repair of the adult body, progressing through the cell cycle is regulated primarily by two interacting processes. (1)Production of, and responses to, growth factors that generally speed up the cell cycle; (2)Intracellular checkpoints that stop the cell cycle if problems such as mutations in the DNA or misalignment of the chromosomes have occurred. Most cancers develop because one of both of these processes goes awry. Many different molecules control the cell cycle; Porto-oncogenes:Any gene whose proteins tends to promote mitotic cell division if called a proton-oncogene. The genes for growth factors, grow factor receptors, and some cyclins and Cdks are proton-oncogenes. In most cases, progress through the cell cycle beings when a growth-stimulating protein such as epidermal growth factor (EGF) binds to a receptor on the surface of a cell. This stimulates the synthesis of cyclins which bind to Cdks and activate them. Thus, these proton-oncogenes are essential to the normal control of the cell cycle. Tumor suppressor genes:The protein products of tumor suppressor genes prevent uncontrolled cell division and the production of daughter cells with mutated DNA, both of which are common in tumors. Cdks regulate the activity of other proteins by adding a phosphate group to them. One such protein is Rb. Normally, Rb inhibits transcription of several genes whose protein products are required for DNA synthesis. Phosphorylation of Rb by Cdks relieves this inhibition in the G, phase of the cell cycle, allowing the cell to proceed to the S phase and replicate its DNA. This chain of events, from growth faction stimulation to phosphorylation of Rb, ensures that the cell cycle starts up only when the body needs it to. Another tumor suppressor protein, called P53 monitors the integrity of the cells DNA and indirectly regulates Rb activity. Healthy cells with intact DNA, contain little P53. However, when DNA has been damaged (for example by ultraviolet rays in sunlight), P53 levels rise. The P53 proteins that inhibit Cdks. If Cdks are inhibited then Rb is not phosphorylated and DNA synthesis is blocked; this prevents the cell from producing daughter cells with damaged DNA. The P53 stimulated the synthesis of DNA repair enzymes. After the DNA has been repaired, P53 levels decline, Cdks become active, Rb becomes phosphorylated and the cell enters the S phase. If the DNA cannot be repaired, P53 triggers a special from of cell death called apoptosis, in which the cell cuts up its DNA and effectively commits suicide.

the pledge of allegiance Essay -- essays research papers

  Ã‚  Ã‚  Ã‚  Ã‚  The Pledge Of Allegiance   Ã‚  Ã‚  Ã‚  Ã‚  The Pledge of Allegiance was written in 1892 by a man named Francis Bellamy for a children’s magazine called The Youth’s Companion. Mr. Bellamy wanted the flag to fly above every school in America so that children would feel pride and love for their country when reciting the words to the Pledge of Allegiance. That was before the recent September 11, 2001 attacks.   Ã‚  Ã‚  Ã‚  Ã‚  The Pledge of Allegiance is a solemn oath of allegiance or fidelity to the U.S. I pledge allegiance, has always meant a strong devotion to or a solemn promise of loyalty of a citizen to his or her government. This is nothing but the truth since September 11,2001. More than ever have we all seen the strong devotion and dedication to this great country. In the first few days after the terrorist’s attacks you couldn’t buy an American flag anywhere. Everyone had in some way symbolized his or her strong patriotism, in a visual sense and an emotional sense. It didn’t seem to have the strong feeling that accompanied the strong words until recent.   Ã‚  Ã‚  Ã‚  Ã‚  To the flag, a piece of cloth varying in size, shape, color, and design, usually attached to one end of a staff or cord and used as the symbol of a nation, state or organization. Not these days. The flag that we are talking about is not about size, shape and color. A symbol of a nation is closer but doesn’t capture it. What we are clear... the pledge of allegiance Essay -- essays research papers   Ã‚  Ã‚  Ã‚  Ã‚  The Pledge Of Allegiance   Ã‚  Ã‚  Ã‚  Ã‚  The Pledge of Allegiance was written in 1892 by a man named Francis Bellamy for a children’s magazine called The Youth’s Companion. Mr. Bellamy wanted the flag to fly above every school in America so that children would feel pride and love for their country when reciting the words to the Pledge of Allegiance. That was before the recent September 11, 2001 attacks.   Ã‚  Ã‚  Ã‚  Ã‚  The Pledge of Allegiance is a solemn oath of allegiance or fidelity to the U.S. I pledge allegiance, has always meant a strong devotion to or a solemn promise of loyalty of a citizen to his or her government. This is nothing but the truth since September 11,2001. More than ever have we all seen the strong devotion and dedication to this great country. In the first few days after the terrorist’s attacks you couldn’t buy an American flag anywhere. Everyone had in some way symbolized his or her strong patriotism, in a visual sense and an emotional sense. It didn’t seem to have the strong feeling that accompanied the strong words until recent.   Ã‚  Ã‚  Ã‚  Ã‚  To the flag, a piece of cloth varying in size, shape, color, and design, usually attached to one end of a staff or cord and used as the symbol of a nation, state or organization. Not these days. The flag that we are talking about is not about size, shape and color. A symbol of a nation is closer but doesn’t capture it. What we are clear...

Hum/105 World Mythology

Many volcanoes and mountains stretch across the world; however, all volcanoes and mountains are not considered sacred. Mount Fuji and Mauna Kea function as sacred places rich with mythical elements that have a functional role in culture, and are comparatively similar. Mount Fuji was once a sacred place only accessible to men for spiritual enlightenment, but is no longer strict on visitation. Although ceremonies remain held during climbing season to this day, many people view the ritual as more a cultural experience instead of a religious one. Japan has two other mountains, but neither is as sacred or rich with religious and mythological Japanese culture. Mount Fuji is one of the most sacred places in the Japanese culture. Every year thousands climb to the shrine every summer. Traditionally the climb to the shrine on the peak was a religious movement and women were not allowed to make the journey. This climb usually required the wearing of white robes (O'Meara, 2006). Today thousands come to climb generally during â€Å"climbing† season from July 1st to August 26th. Many believe that this place is very sacred and many believe it to be spiritual (O'Meara, 2006). People commonly believe that ascending this mountaintop is to bring luck and the more one climbs the better. The mythic belief retains empowerment because the mountain also serves as a national emblem (Leonard & McClure, 2004, p. 350). Some have climbed at least 100 times. At the start of each climbing season two religious sects hold sacred ceremonies to begin climbing season (O’Meara, 2006). Some have marathons ascending and descending the mountain. Many believe it to be unlucky to ascend any other sacred mountaintop. Climbing Mt. Fuji is one of religious tradition. Tradition states that the mountain is split into three parts from peak to base. The grassy areas represent the mundane world. The forest line represents the transient line between this world and the world of the gods. The burned areas with a thick layer of volcanic ash represent the realm of the gods and Buddha. The idea of ascending and descending the mountain represent travels between the world of the living and the dead. With each passage one could receive purity and have the sins of this world washed away (Fujisan, 2009). Shintoists believe Mount Fuji is sacred to the goddess Sengen-Sama. They also believe the mountain itself to be an embodiment of nature. Another religious sect believes that the mountain itself is a sacred being which contains a soul. The Buddhists believe the mountain is a gateway to another world (Sacred-Destinations, 2009). Mount Fuji is a sacred place and has been since the first inhabitants of Japan. Buddhists believe the mountain came to be around 286 BC after an earthquake that formed the mountain as well as the Lake Blwa, the largest lake in Japan (Sacred-Destinations, 2009). This mountain is a very sacred part of Japanese religion and for years people treated it as such. Today it is more of an attraction and the religious meaning has been lost a little. Mount Fuji seems to be more of a tourist hotspot than a spiritual place, one in which souvenirs can be bought. Mt. Fuji or Fuji San refers to the most sacred mountain in Japan. Mt. Fuji is such a natural symbol and sacred not only to the Shinto and Buddhist but also for most Japanese people. The name â€Å"Fuji† is a local Ainu word that means â€Å"deity of fire† because of the often-volcanic eruptions (Mount Fuji, 2011). The Japanese built a shrine about 800 A. D. to the gods to help calm the erupting volcano. Mount Fuji later became home to a Shinto goddess Konohano Sakuya Hime â€Å"the Goddess of the Flowering Trees. † The Shinto goddess Koyasusama is also known as the goddess who grants easy childbirth. The Shinto goddess has â€Å"shrines at the base and summit of Fuji† where there is a fire ceremony at the conclusion of the climbing season (New World Encyclopedia, 2009). The Fujiyoshida’s Sengen Shrine is the main Sengen Shrine positioned on the north side of the mountain. The shrine stands in a dark forest and is set off the road lined with stone lanterns and tall cedar trees. In the past the Shrine was a starting point for climbing Mt. Fuji, and these hikers would start their ascent with a prayer at the shrine. Buddhist found Fuji as a â€Å"symbol of meditation† and calls its â€Å"summit zenjo,† that is a Buddhist term that describes perfection of a meditative state (Mount Fuji, 2011). Japanese Buddhists revere the mountain as a gateway to another world. â€Å"Shugendo practitioners established the first climbing route to lead pilgrims to Fuji’s summit† (Mount Fuji, 2011). Today pilgrims continue to climb Mount Fuji. Some stop to worship at the shrine of Konohana Sakuya Hime, pray at the summit altars, or ritually circumambulate the volcano’s crater† (Mount Fuji, 2011). Aokigahara, also known as the Sea of Trees is another sacred and mythological place that lies at the base of Mt. Fuji. The Sea of Trees are associated with demons in Japanese mythology, haunted by the ghost of people left to die. Mauna Kea is a tr aditional mythical place that compares to Mount Fuji. Mauna Kea is a volcano found on the big Island of Hawaii. In Hawaiian mythology, the peaks of the island of Hawaii are sacred. Only high-ranking tribal chiefs were allowed to visit the peak. Mount Fuji is the central figure in the neisho-e work. The Japanese consider Mt. Fuji to be sacred and is a symbol of national identity (Wikipedia, n. d. ). Mount Fuji is also considered to be a symbol of beauty. The mountains are also a sacred place because the higher the mountain the closer the mountain’s reach to heaven. Some sacred mountain can sometimes be just a mythical thought, depending on the meaning or the purpose of the mountain. Mount Fuji, located in Japan, is the highest mountain with an active volcano. Japan has Three Holy Mountains. Mount Fuji is the mountain the sightseers go see when they are in Japan. The other two mountains in Japan are Mount Tate and Mount Haku. Some people think that the meaning of Fuji is immortal, but no proof has been determined on that issue. Many Japanese writers have used Mount Fuji in their artwork, literature, and as a background picture in several movies. Mount Fuji was sacred to the point that woman were not allowed to go to the mountain. The volcano inside Mount Fuji is currently said to be active, but has a very slim chance of erupting. Mauna Kea is also considered to be the most sacred mountain in Hawaii. The tribal chiefs were the only ones allowed at the top of the mountain. Mauna Kea is one of the best sites that people can visit for astronomical purposes. Mauna Kea is an inactive volcano, unlike Mount Fuji, and is among five other volcanoes in Hawaii. Hawaiian Law implements visitor restrictions on Mauna Kea. Mauna Kea is sacred, and portrayed as the first born of the father of the sky (Wakea) and the mother of the earth (Papa). Mount Fuji and Mauna Kea are active volcanoes. Both volcanoes are sacred places where tribal chiefs are the only ones allowed to go to the top. The mountains are sacred because of developing the highest point closest to heaven. Mount Fuji last erupted in 1707-08. Mauna Kea last erupted was about 4,600 years ago. Both mountains have that attractive cone shape, and are hotspots of their location. Once a sacred Japanese religious site, Mount Fuji has become more of a tourist attraction. This volcano became a shrine to Gods, and later to the Goddess of the flowering trees. Similar to Mount Fuji in sacredness and Goddess mythology is Mauna Kea, another volcanic mountain. Mauna Kea’s myth embodies the mountain as Poliahu the Snow Goddess, the first child of the sky father and earth mother (Lovingthebigisland’s Weblog, 2009). Both sites are rich with mythology, culture, and both are sacred places. Although Mauna Kea has limits on who may ascend, Mount Fuji is open for all to climb. Both Mount Fuji and Mauna Kea retained their sacred status because of their heights being closest to heaven. References Fujisan (2009). Mt. Fuji and religious beliefs. Retrieved from http://www. fujisan-3776. jp/english/religiouis_beliefs/religiouis_beliefs. html. Leonard, S. , & McClure, M. (2004). Myth & knowing: An introduction to world mythology. New York: McGraw-Hill. Lovingthebigisland’s Weblog. (2009). The Hawaiian snow goddess poliahu and the summit of mauna kea. Retrieved July 30, 2011, from http://lovingthebigisland. wordpress. com/2009/02/05/the-hawaiian-snow-goddess-poliahu-and-the-summit-of-mauna-kea/. Mount Fuji. (n. d. ). Wikipedia: The free encyclopedia. Retrieved July 29, 2011, from http://en. wikipedia. org/wiki/Mount_Fuji. New World Encyclopedia. (2009). Mount Fuji. Retrieved July 29, 2011, from http://www. ewworldencyclopedia. org/entry/Mt. _Fuji O'Meara, D. (2006). Mount Fuji. Faces (07491387), 22(5), 6. Retrieved from EBSCOhost History. com (1994-2009). Mount Fuji. Retrieved from http://www. history. com/topics/mount-fuji. Sacred-Destinations (2009). Mount Fuji. Retrieved from http://www. sacred-destinations. com/japan/mount-fuji. Sacred Land. (2011). Mount Fuji. Retrieved July 29, 2011, from http://www. sacredland . org/mount-fuji/. Wikipedia. (n. d. ) The great wave off kanagawa. ASK. Retrieved July 29, 2011, from http://www. ask. com/wiki/The_Great_Wave_off_Kanagawa.

Essay on To an Athlete Dying Young Poetry Analysis

Sydney Walcher Instructor, Lisa Ward English 1213 8 April 2013 To an Athlete Dying Young A.E. Housman was a poet born in 1859 who became very successful during his lifetime. â€Å"To an Athlete Dying Young† represents the theme of glory is fleeting by illustrating the point that if a successful athlete dies young, they will not have to worry about their glory of victory fading. They can rest in peace knowing they will be remembered at their athletic peak when they were successful and victorious. They will not have to go through the pain of watching their fame disappear or whither out with time. In this poetic masterpiece, Housman pulls together figurative language, sound devices, and structure to illustrate that glory is fleeting through a†¦show more content†¦Another example is â€Å"Today, the road all runners come† because of road and runner. Rhyme is similarity of sound between words or the endings of words when used at the end of a line of poetry. The rhyme scheme of â€Å"To an Athlete Dying Young† is ABAB. This means that the last wor d of every two lines rhymes. For example, â€Å"So set, before its echoes fade,/The fleet foot on the sill of shade,/And hold to the lintel up/The still-defended challenge cup.† This is an excellent demonstration of the ABAB rhyme scheme because â€Å"fade† and â€Å"shade† rhymes, as does â€Å"up† and â€Å"cup.† In â€Å"To an Athlete Dying Young,† Housman uses iambic tetrameter, which refers to a line that is four iambic feet long, to create a lyric poem that can otherwise be known as an elegy since it praises an athlete that died young. Iambic tetrameter affects the beat of the words and how they flow together gracefully. Iambic tetrameter consists of a stressed syllable followed by an unstressed syllable. Most lines in these poems tend to have eight syllables. However, lines thirteen and fourteen, â€Å"Eyes the shady night has shut/Cannot see the record cut,† stray from iambic tetrameter to trochaic tetrameter, one stressed syl lable plus one unstressed syllable in four feet, with catalexis, which is an incomplete foot at the end of a line. The literary masterpiece, â€Å"To an Athlete Dying Young,† uses figurative language, sound devices, and structure to illustrate a poemShow MoreRelatedThe Death Of An Athlete Dying Young1640 Words   |  7 PagesHousman s To An Athlete Dying Young A. E. Housman s To an Athlete Dying Young, also known as Lyric XIX in A Shropshire Lad, holds as its main theme the premature death of a young athlete as told from the point of view of a friend serving as pall bearer. The poem reveals the concept that those dying at the peak of their glory or youth are really quite lucky. The first few readings of To an Athlete Dying Young provides the reader with an understanding of Housman s view of death. AdditionalRead More An Analysis Of British Literature Essay2728 Words   |  11 Pages An Analysis of British Literature nbsp;nbsp;nbsp;nbsp;nbsp;Death is inevitable and what happens after death will always be a mystery to the living. For this reason, the afterlife has always been a topic which artists have chosen to explore in their works. Throughout the chronology of British literature, artists have used societys views as a basis to examine the afterlife, and look at it in new ways. The afterlife has been a theme in British Literature from the Anglo-Saxon period of BeowulfRead MoreGp Essay Mainpoints24643 Words   |  99 Pagescan easily get broadcasted to a global audience †¢ Publishers want to ensure that their books sell *quality check* †¢ Any hack can put up his dribbling on Fictionpress.net †¢ Any angst-filled teenager can put up his or her macabre, misspelt poetry online. †¢ Anyone can masquerade a superstition for scientific truth and create a website to scare similarly weak-minded netizens Mainstream BAD: Profit motive and Government-regulated - reliability †¢ â€Å"Don’t let the facts get in the way ofRead MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 PagesUniversity Christine Day, Eastern Michigan University Emmeline de Pillis, University of Hawaii, Hilo Kathy Lund Dean, Idaho State University Roger Dean, Washington Lee University Robert DelCampo, University of New Mexico Kristen Detienne, Brigham Young University Doug Dierking, University of Texas at Austin Cynthia Doil, Southern Illinois University Jennifer Dose, Messiah College Ceasar Douglas, Florida State University David Duby, Liberty University Ken Dunegan, Cleveland State University Michael